Abstract: In view of the existing instability problem of the slope of Shengli East No.2 open-pit mine, a calculation model for soft-hard interbedded down dip rock slope is established by utilizing Phase2D finite element numerical software, and the stability and failure mode under conditions such as cohesion, internal friction angle, rock strata inclination angle and others are analyzed. The results indicate that as the cohesion and internal friction angle of soft and hard rock strata increase, the slope safety coefficient increases from 1.23 to about 1.62, the shear zone exhibits a circular arc shape, mainly appearing in weak rock strata and tangent to the junction between soft and hard rock strata; As the rock strata inclination angle increases, the total displacement of the slope shows a nonlinear change, when the change range of rock strata inclination angle is 0-30°, the maximum total displacement of the slope decreases from 11.4 cm to 2.9 cm, when the change range of rock strata inclination angle is 50-90°, the maximum total displacement of the slope gradually increases from 6.0 cm to 83.3 cm; The safety coefficient first decreases and then increases with the rock strata inclination angle. The research results show that the soft-hard interbedded down dip rock slope is prone to occur landslide near weak layers, the rock strata inclination angle has a relatively large impact on slope stability, and the slope stability decreases obviously under specific inclination angles.