Abstract: In view of the problems of fault development of withdrawal channels, weak roof and floor, and difficulty in controlling surrounding rock stability during the final mining stage of fully mechanized mining, a support force-stability response model is constructed combined with actual measured data. Based on the elastic-plastic theory, the deformation mechanism of roof and floor is analyzed, a joint support system of "anchor rod+anchor cable+steel mesh" is designed, and relevant parameter calculations are completed. During the construction process, a combination layout of hydraulic and pneumatic drilling rig is adopted, as well as resin medicine roll + full-length bonded anchor cable process, the initial bearing capacity and coordination are effectively improved. The monitoring results indicate that the roof subsidence amount is controlled within 100 mm, and the pulling force of anchor rod and the tension force of anchor cable is averagely improved by 49.0% and 21.0%, respectively. The cross-section convergence rate is decreased by 46.4%, and the structure stability of surrounding rock is significantly enhanced. This research result provides technical support and design basis for the support of withdrawal channels under similar geological conditions.