Abstract: In view of the engineering background of Binxian Shuiliandong Coal Mine, which has a burial depth of 420 m and significant high-level structural stress, 15 sets of protolith 3D geostress data are obtained by adopting trepan boring stress relief method, through 3D inversion, the maximum horizontal principal stress in the synclinal axis reaches 19.7 MPa, and a structural controlled stress concentration area with a stress gradient of 4.2 MPa are revealed. Based on this boundary condition, FLAC^3D stoping simulation is carried out, it is concluded that the peak value of advanced support pressure in the working face is 18.7 MPa, with an influence range of about 65 m, and the high energy density area is highly coincident with the pressure peak area. The on-site monitoring indicates that under the traditional rigid support, the increase of anchor cable load peak exceeds 100 kN, and the roadway convergence rate is 0.35-0.48 mm/d; After adopting the "unloading-supporting-yielding" coupling prevention and control technology, the increase of anchor cable load is controlled within 30 kN, the roadway convergence rate is decreased to below 0.15 mm/d, microseismics are mainly characterized by low-energy and high-frequency releases, and without significant energy accumulation. This technology can significantly weakens stress concentration and energy accumulation, and achieves advanced prevention and control of dynamic pressure disasters in high stress areas.